Monday, July 25, 2011

In 2001, discovered hepatitis B. clinic is always absent. Dynamics of positive seroconversion after lamivudine, HbsAg - neg, antiHbsAg - Assume DNA - neg serum for 2 years, but in blood cells - DNA - poorly put. Quantifying the load - less than 500 copies / ml. Tell me, pozhalysta, mlzhet whether this evidence of an emerging pastes infection or not, what is the minimum threshold (sensitivity) in viral load (less than 500 - it could be 10 copies, and can t 490) that can be done to reduce this indicator to undetectable values, and possible?. Thanks in advance.

Respond Karshieva Anna V., hepatology, gastroenterology, hepatology and gastroenterology clinic Medal Very rare result of treatment with lamivudine. Especially seroconversion to HBsAg. I think that there is reason to talk about the pastes infection. With regard to the threshold of viral load test with PCR in blood cells (in what? Leukocytes, red blood cells), it is less than 500 copies / ml, or more precisely a system test can not identify. If DNA is weakly positive in leukocytes, it is partly, too, can be placed into the jaws of infection in this case. Enhance immunity by entering possible dose of the vaccine against hepatitis B. A similar question: ... PCR. Results: Hepatitis B quantitative Less than 310 square copies of DNA / ml.Gepatit With quantitative less than 210 in the cube (less than 500 IU / ml) RNA copies / ml.Eto minimum or maximum viral load ...

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